Do not use anti-diarrhea or opioid medications if you have the following symptoms because these products may make them worse. This condition may occur during treatment or even weeks to months after treatment has stopped. This medication may rarely cause a severe intestinal condition (Clostridium difficile-associated diarrhea) due to a resistant bacteria. Get medical help right away if you develop symptoms of lung problems, including: persistent cough, chest pain, shortness of breath/trouble breathing, joint/muscle pain, bluish/purplish skin. Lung problems may occur within the first month of treatment or after long-term use of nitrofurantoin (generally for 6 months or longer). This medication may rarely cause very serious (possibly fatal) lung problems. Seek immediate medical attention if you develop the following rare but very serious side effects: numbness/tingling of the hands/feet, unusual muscle weakness. Tell your doctor right away if any of these rare but very serious side effects occur: eye pain, vision changes, mental/mood changes, persistent/severe headaches, new signs of infection (e.g., fever, persistent sore throat), easy bruising/bleeding. Therefore, seek immediate medical attention if you notice dark urine along with any of the following symptoms: persistent nausea/vomiting, stomach/abdominal pain, yellowing eyes/skin, tiredness, fast/pounding heartbeat. However, dark brown urine can also be a sign of rare side effects (liver problems or anemia). This is usually a harmless, temporary effect and will disappear when the medication is stopped. This medication may cause your urine to turn dark yellow or brown in color. Many people using this medication do not have serious side effects. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.
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